Energy coupling in DNA gyrase and the mechanism of action of novobiocin

Escherichia coli DNA gyrase catalyzes negative supercoiling of closed duplex DNA at the expense of ATP. Two additional activities of the enzyme that have illuminated the energy coupling component of the supercoiling reaction are the DNA-dependent hydrolysis of ATP to ADP and P(i) and the alteration...

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Εκδόθηκε σε:	Proc Natl Acad Sci U S A
Κύριοι συγγραφείς:	Sugino, Akio, Higgins, N. Patrick, Brown, Patrick O., Peebles, Craig L., Cozzarelli, Nicholas R.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	National Academy of Sciences 1978
Θέματα:	Biological Sciences: Biochemistry
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336216/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/368801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.10.4838
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