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Characterization of the Niemann-Pick C pathway in alveolar type II cells and lamellar bodies of the lung

The Niemann-Pick C (NPC) pathway plays an essential role in the intracellular trafficking of cholesterol by facilitating the release of lipoprotein-derived sterol from the lumen of lysosomes. Regulation of cellular cholesterol homeostasis is of particular importance to lung alveolar type II cells be...

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Detalles Bibliográficos
Main Authors: Roszell, Blair R., Tao, Jian-Qin, Yu, Kevin J., Huang, Shaohui, Bates, Sandra R.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362154/
https://ncbi.nlm.nih.gov/pubmed/22367786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00383.2011
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