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Mitochondrial reactive oxygen species and calcium uptake regulate activation of phagocytic NADPH oxidase

Production of superoxide (O(2)(·−)) by NADPH oxidases contributes to the development of hypertension and atherosclerosis. Factors responsible for activation of NADPH oxidases are not well understood; interestingly, cardiovascular disease is associated with both altered NADPH oxidase activity and age...

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Détails bibliographiques
Auteurs principaux: Dikalov, Sergey I., Li, Wei, Doughan, Abdulrahman K., Blanco, Raul R., Zafari, A. Maziar
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362147/
https://ncbi.nlm.nih.gov/pubmed/22442197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00842.2010
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