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Acid catalysis of the formation of the slow-folding species of RNase A: Evidence that the reaction is proline isomerization

Unfolded RNase A is known to contain an equilibrium mixture of two forms, a slow-folding form (U(1)) and a fast-folding form (U(2)). If U(1) is produced after unfolding by the slow cis-trans isomerization of proline residues about X-Pro imide bonds, then the formation of U(1) should be catalyzed by...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Schmid, Franz X., Baldwin, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336200/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/283390/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.10.4764
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