Acid catalysis of the formation of the slow-folding species of RNase A: Evidence that the reaction is proline isomerization
Unfolded RNase A is known to contain an equilibrium mixture of two forms, a slow-folding form (U(1)) and a fast-folding form (U(2)). If U(1) is produced after unfolding by the slow cis-trans isomerization of proline residues about X-Pro imide bonds, then the formation of U(1) should be catalyzed by...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1978
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336200/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/283390/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.10.4764 |
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