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Isolation of two interferon-induced translational inhibitors: a protein kinase and an oligo-isoadenylate synthetase.

Large-scale purification of translational inhibitors present in interferon-treated mouse L cells, but not in untreated cells, led to the isolation of two interferon-induced activities. One is a protein kinase system that is activatable by double-stranded RNA and ATP and that phosphorylates a Mr 67,0...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zilberstein, A, Kimchi, A, Schmidt, A, Revel, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336194/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/283387/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.10.4734
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