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Isolation of two interferon-induced translational inhibitors: a protein kinase and an oligo-isoadenylate synthetase.

Large-scale purification of translational inhibitors present in interferon-treated mouse L cells, but not in untreated cells, led to the isolation of two interferon-induced activities. One is a protein kinase system that is activatable by double-stranded RNA and ATP and that phosphorylates a Mr 67,0...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Zilberstein, A, Kimchi, A, Schmidt, A, Revel, M
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1978
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336194/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/283387/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.10.4734
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