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Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification

Heterotopic ossification is a debilitating condition that can result from traumatic injury, surgery, or genetic disease. We investigated the cellular origins of heterotopic skeletogenesis in the mouse using lineage tracing and bioassays of heterotopic ossification based on intramuscular transplantat...

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Detalhes bibliográficos
Main Authors: Wosczyna, Michael N., Biswas, Arpita A., Cogswell, Catherine A., Goldhamer, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361573/
https://ncbi.nlm.nih.gov/pubmed/22307978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1562
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