Predicting warfarin dosage in European–Americans and African–Americans using DNA samples linked to an electronic health record

AIM: Warfarin pharmacogenomic algorithms reduce dosing error, but perform poorly in non-European–Americans. Electronic health record (EHR) systems linked to biobanks may allow for pharmacogenomic analysis, but they have not yet been used for this purpose. PATIENTS & METHODS: We used BioVU, the V...

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Hauptverfasser: Ramirez, Andrea H, Shi, Yaping, Schildcrout, Jonathan S, Delaney, Jessica T, Xu, Hua, Oetjens, Matthew T, Zuvich, Rebecca L, Basford, Melissa A, Bowton, Erica, Jiang, Min, Speltz, Peter, Zink, Raquel, Cowan, James, Pulley, Jill M, Ritchie, Marylyn D, Masys, Daniel R, Roden, Dan M, Crawford, Dana C, Denny, Joshua C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361510/
https://ncbi.nlm.nih.gov/pubmed/22329724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.11.164
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