Predicting warfarin dosage in European–Americans and African–Americans using DNA samples linked to an electronic health record

AIM: Warfarin pharmacogenomic algorithms reduce dosing error, but perform poorly in non-European–Americans. Electronic health record (EHR) systems linked to biobanks may allow for pharmacogenomic analysis, but they have not yet been used for this purpose. PATIENTS & METHODS: We used BioVU, the V...

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Detalhes bibliográficos
Main Authors: Ramirez, Andrea H, Shi, Yaping, Schildcrout, Jonathan S, Delaney, Jessica T, Xu, Hua, Oetjens, Matthew T, Zuvich, Rebecca L, Basford, Melissa A, Bowton, Erica, Jiang, Min, Speltz, Peter, Zink, Raquel, Cowan, James, Pulley, Jill M, Ritchie, Marylyn D, Masys, Daniel R, Roden, Dan M, Crawford, Dana C, Denny, Joshua C
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361510/
https://ncbi.nlm.nih.gov/pubmed/22329724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.11.164
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