iNOS-Derived Nitric Oxide Stimulates Osteoclast Activity and Alveolar Bone Loss in Ligature-Induced Periodontitis in Rats

BACKGROUND: Inflammatory stimuli activate inducible nitric oxide synthase (iNOS) in a variety of cell types, including osteoclasts (OC) and osteoblasts, resulting in sustained NO production. In this study, we evaluate the alveolar bone loss in rats with periodontitis under long-term iNOS inhibition,...

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Bibliografische gegevens
Hoofdauteurs: Herrera, Bruno S., Martins-Porto, Rodrigo, Maia-Dantas, Aline, Campi, Paula, Spolidorio, Luis C., Costa, Soraia K.P., Van Dyke, Thomas E., Gyurko, Robert, Muscara, Marcelo N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361509/
https://ncbi.nlm.nih.gov/pubmed/21417589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1902/jop.2011.100768
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