Janus-faced liposomes enhance antimicrobial innate immune response in Mycobacterium tuberculosis infection

We have generated unique asymmetric liposomes with phosphatidylserine (PS) distributed at the outer membrane surface to resemble apoptotic bodies and phosphatidic acid (PA) at the inner layer as a strategy to enhance innate antimycobacterial activity in phagocytes while limiting the inflammatory res...

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Detalhes bibliográficos
Main Authors: Greco, Emanuela, Quintiliani, Gianluca, Santucci, Marilina B., Serafino, Annalucia, Ciccaglione, Anna Rita, Marcantonio, Cinzia, Papi, Massimiliano, Maulucci, Giuseppe, Delogu, Giovanni, Martino, Angelo, Goletti, Delia, Sarmati, Loredana, Andreoni, Massimo, Altieri, Alfonso, Alma, Mario, Caccamo, Nadia, Di Liberto, Diana, De Spirito, Marco, Savage, Nigel D., Nisini, Roberto, Dieli, Francesco, Ottenhoff, Tom H., Fraziano, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361443/
https://ncbi.nlm.nih.gov/pubmed/22538807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200484109
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