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Amino acid coevolution induces an evolutionary Stokes shift

The process of amino acid replacement in proteins is context-dependent, with substitution rates influenced by local structure, functional role, and amino acids at other locations. Predicting how these differences affect replacement processes is difficult. To make such inference easier, it is often a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pollock, David D., Thiltgen, Grant, Goldstein, Richard A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361410/
https://ncbi.nlm.nih.gov/pubmed/22547823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120084109
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