Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function

Nuclear protein peptidyl-prolyl isomerase Pin1-mediated prolyl isomerization is an essential and novel regulatory mechanism for protein phosphorylation. Therefore, tight regulation of Pin1 localization and catalytic activity is crucial for its normal nuclear functions. Pin1 is commonly dysregulated...

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Bibliografski detalji
Glavni autori: Rangasamy, Velusamy, Mishra, Rajakishore, Sondarva, Gautam, Das, Subhasis, Lee, Tae Ho, Bakowska, Joanna C., Tzivion, Guri, Malter, James S., Rana, Basabi, Lu, Kun Ping, Kanthasamy, Anumantha, Rana, Ajay
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361382/
https://ncbi.nlm.nih.gov/pubmed/22566623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200804109
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