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Activation of 5′-3′ exoribonuclease Xrn1 by cofactor Dcs1 is essential for mitochondrial function in yeast

The scavenger decapping enzyme Dcs1 has been shown to facilitate the activity of the cytoplasmic 5′-3′ exoribonuclease Xrn1 in eukaryotes. Dcs1 has also been shown to be required for growth in glycerol medium. We therefore wondered whether the capacity to activate RNA degradation could account for i...

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Detalhes bibliográficos
Main Authors: Sinturel, Flore, Bréchemier-Baey, Dominique, Kiledjian, Megerditch, Condon, Ciarán, Bénard, Lionel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361377/
https://ncbi.nlm.nih.gov/pubmed/22570495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120090109
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