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Origin of the genetic code: a testable hypothesis based on tRNA structure, sequence, and kinetic proofreading.
We hypothesize that the origin of the genetic code is associated with the structure of the tRNA that existed in primal cells. The sequences of modern tRNA contain correlations which can be understood as "fossil" evidence of the secondary structure of primal tRNA. Kinetic proofreading throu...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1978
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336109/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/279919/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.9.4334 |
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