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Asymmetric positive feedback loops reliably control biological responses

Positive feedback is a common mechanism enabling biological systems to respond to stimuli in a switch-like manner. Such systems are often characterized by the requisite formation of a heterodimer where only one of the pair is subject to feedback. This ASymmetric Self-UpREgulation (ASSURE) motif is c...

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Detalhes bibliográficos
Main Authors: Ratushny, Alexander V, Saleem, Ramsey A, Sitko, Katherine, Ramsey, Stephen A, Aitchison, John D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361002/
https://ncbi.nlm.nih.gov/pubmed/22531117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.10
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