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Engineered myosin VI motors reveal minimal structural determinants of directionality and processivity

Myosins have diverse mechanical properties reflecting a range of cellular roles. A major challenge is to understand the structural basis for generating novel functions from a common motor core. Myosin VI is specialized for processive motion toward the (-) end of actin filaments. We have used enginee...

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Autors principals: Liao, Jung-Chi, Elting, Mary Williard, Delp, Scott L., Spudich, James A., Bryant, Zev
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360974/
https://ncbi.nlm.nih.gov/pubmed/19631216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.07.046
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