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The structure of the myosin VI motor reveals the mechanism of directionality reversal

We have solved a 2.4Å structure of a truncated version of the reverse direction myosin motor, myosin VI, that contains the motor domain and binding sites for two calmodulins. The structure reveals only minor differences in the motor domain as compared to plus-end directed myosins, with the exception...

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Autori principali: Ménétrey, Julie, Bahloul, Amel, Wells, Amber, Yengo, Christopher, Morris, Carl, Sweeney, H. Lee, Houdusse, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762700/
https://ncbi.nlm.nih.gov/pubmed/15944696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03592
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