Načítá se...

Differential Degradation of Full-length and Cleaved Ataxin-7 Fragments in a Novel Stable Inducible SCA7 Model

Spinocerebellar ataxia type 7 (SCA7) is one of nine neurodegenerative disorders caused by expanded polyglutamine repeats, and a common toxic gain-of-function mechanism has been proposed. Proteolytic cleavage of several polyglutamine proteins has been identified and suggested to modulate the polyglut...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Yu, Xin, Ajayi, Abiodun, Boga, Narasimha Rao, Ström, Anna-Lena
Médium: Artigo
Jazyk:Inglês
Vydáno: Humana Press Inc 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360856/
https://ncbi.nlm.nih.gov/pubmed/22367614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-012-9722-8
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!