A Common Missense Variant in the ATP Receptor P2X7 Is Associated with Reduced Risk of Cardiovascular Events

BACKGROUND AND PURPOSE: Extracellular adenosine triphosphate (ATP) regulates inflammatory cells by activation of the P2X(7) receptor. We hypothesized that polymorphisms in P2RX7 influence the risk of ischemic heart disease (IHD), ischemic stroke (IS) and cardiovascular risk factors and tested this h...

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書誌詳細
主要な著者: Gidlöf, Olof, Smith, J. Gustav, Melander, Olle, Lövkvist, Håkan, Hedblad, Bo, Engström, Gunnar, Nilsson, Peter, Carlson, Joyce, Berglund, Göran, Olsson, Sandra, Jood, Katarina, Jern, Christina, Norrving, Bo, Lindgren, Arne, Erlinge, David
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360776/
https://ncbi.nlm.nih.gov/pubmed/22662160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037491
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