A Common Missense Variant in the ATP Receptor P2X7 Is Associated with Reduced Risk of Cardiovascular Events

BACKGROUND AND PURPOSE: Extracellular adenosine triphosphate (ATP) regulates inflammatory cells by activation of the P2X(7) receptor. We hypothesized that polymorphisms in P2RX7 influence the risk of ischemic heart disease (IHD), ischemic stroke (IS) and cardiovascular risk factors and tested this h...

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Autores principales: Gidlöf, Olof, Smith, J. Gustav, Melander, Olle, Lövkvist, Håkan, Hedblad, Bo, Engström, Gunnar, Nilsson, Peter, Carlson, Joyce, Berglund, Göran, Olsson, Sandra, Jood, Katarina, Jern, Christina, Norrving, Bo, Lindgren, Arne, Erlinge, David
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360776/
https://ncbi.nlm.nih.gov/pubmed/22662160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037491
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