ATP Induced Brain-Derived Neurotrophic Factor Expression and Release from Osteoarthritis Synovial Fibroblasts Is Mediated by Purinergic Receptor P2X4

Brain-derived neurotrophic factor (BDNF), a neuromodulator involved in nociceptive hypersensitivity in the central nervous system, is also expressed in synoviocytes of osteoarthritis (OA) and rheumatoid arthritis (RA) patients. We investigated the role of P2 purinoreceptors in the induction of BDNF...

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Detaylı Bibliyografya
Asıl Yazarlar: Klein, Kerstin, Aeschlimann, André, Jordan, Suzana, Gay, Renate, Gay, Steffen, Sprott, Haiko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360754/
https://ncbi.nlm.nih.gov/pubmed/22715356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036693
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