Central Role of SREBP-2 in the Pathogenesis of Osteoarthritis

BACKGROUND: Recent studies have implied that osteoarthritis (OA) is a metabolic disease linked to deregulation of genes involved in lipid metabolism and cholesterol efflux. Sterol Regulatory Element Binding Proteins (SREBPs) are transcription factors regulating lipid metabolism with so far no associ...

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Detalhes bibliográficos
Main Authors: Kostopoulou, Fotini, Gkretsi, Vasiliki, Malizos, Konstantinos N., Iliopoulos, Dimitrios, Oikonomou, Pagona, Poultsides, Lazaros, Tsezou, Aspasia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360703/
https://ncbi.nlm.nih.gov/pubmed/22662110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035753
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