Central Role of SREBP-2 in the Pathogenesis of Osteoarthritis

BACKGROUND: Recent studies have implied that osteoarthritis (OA) is a metabolic disease linked to deregulation of genes involved in lipid metabolism and cholesterol efflux. Sterol Regulatory Element Binding Proteins (SREBPs) are transcription factors regulating lipid metabolism with so far no associ...

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Bibliographische Detailangaben
Hauptverfasser: Kostopoulou, Fotini, Gkretsi, Vasiliki, Malizos, Konstantinos N., Iliopoulos, Dimitrios, Oikonomou, Pagona, Poultsides, Lazaros, Tsezou, Aspasia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360703/
https://ncbi.nlm.nih.gov/pubmed/22662110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035753
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