Central Role of SREBP-2 in the Pathogenesis of Osteoarthritis

BACKGROUND: Recent studies have implied that osteoarthritis (OA) is a metabolic disease linked to deregulation of genes involved in lipid metabolism and cholesterol efflux. Sterol Regulatory Element Binding Proteins (SREBPs) are transcription factors regulating lipid metabolism with so far no associ...

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Autori principali: Kostopoulou, Fotini, Gkretsi, Vasiliki, Malizos, Konstantinos N., Iliopoulos, Dimitrios, Oikonomou, Pagona, Poultsides, Lazaros, Tsezou, Aspasia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360703/
https://ncbi.nlm.nih.gov/pubmed/22662110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035753
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