The KRAS-Variant Is Associated with Risk of Developing Double Primary Breast and Ovarian Cancer

PURPOSE: A germline microRNA binding site-disrupting variant, the KRAS-variant (rs61764370), is associated with an increased risk of developing several cancers. Because this variant is most strongly associated with ovarian cancer risk in patients from hereditary breast and ovarian families (HBOC), a...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Pilarski, Robert, Patel, Divya A., Weitzel, Jeffrey, McVeigh, Terri, Dorairaj, Jemima J., Heneghan, Helen M., Miller, Nicola, Weidhaas, Joanne B., Kerin, Michael J., McKenna, Megan, Wu, Xifeng, Hildebrandt, Michelle, Zelterman, Daniel, Sand, Sharon, Shulman, Lee P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360659/
https://ncbi.nlm.nih.gov/pubmed/22662244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037891
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares