Inhibition of Neuroblastoma Tumor Growth by Targeted Delivery of MicroRNA-34a Using Anti-Disialoganglioside GD(2) Coated Nanoparticles

BACKGROUND: Neuroblastoma is one of the most challenging malignancies of childhood, being associated with the highest death rate in paediatric oncology, underlining the need for novel therapeutic approaches. Typically, patients with high risk disease undergo an initial remission in response to treat...

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Hlavní autoři: Tivnan, Amanda, Orr, Wayne Shannon, Gubala, Vladimir, Nooney, Robert, Williams, David E., McDonagh, Colette, Prenter, Suzanne, Harvey, Harry, Domingo-Fernández, Raquel, Bray, Isabella M., Piskareva, Olga, Ng, Catherine Y., Lode, Holger N., Davidoff, Andrew M., Stallings, Raymond L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360657/
https://ncbi.nlm.nih.gov/pubmed/22662276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038129
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