EMT and Stem Cell-Like Properties Associated with HIF-2α Are Involved in Arsenite-Induced Transformation of Human Bronchial Epithelial Cells

BACKGROUND: Arsenic is well-established as a human carcinogen, but the molecular mechanisms leading to arsenic-induced carcinogenesis are complex and elusive. It is not been determined if the epithelial-mesenchymal transition (EMT) and stem cell-like properties contribute in causing to carcinogen-in...

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Detalhes bibliográficos
Main Authors: Xu, Yuan, Li, Yuan, Pang, Ying, Ling, Min, Shen, Lu, Yang, Xiaojun, Zhang, Jianping, Zhou, Jianwei, Wang, Xinru, Liu, Qizhan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360629/
https://ncbi.nlm.nih.gov/pubmed/22662215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037765
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