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Hypercholesterolemic LDL receptor-deficient mice mount a neutrophilic response to tuberculosis despite the timely expression of protective immunity

The prevalence of hypercholesterolemia is rising in industrialized and developing countries. We reported previously that host defense against Mtb was impaired by hypercholesterolemia in ApoE(−/−) mice, raising the possibility that people with HC could be more vulnerable to TB. The present study exam...

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Hlavní autoři: Martens, Gregory W., Vallerskog, Therese, Kornfeld, Hardy
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Leukocyte Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360472/
https://ncbi.nlm.nih.gov/pubmed/22227965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0311164
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