SerpinB1 protects the mature neutrophil reserve in the bone marrow

SerpinB1 is among the most efficient inhibitors of neutrophil serine proteases—NE, CG, and PR-3—and we investigated here its role in neutrophil development and homeostasis. We found that serpinB1 is expressed in all human bone marrow leukocytes, including stem and progenitor cells. Expression levels...

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Bibliografiske detaljer
Main Authors: Benarafa, Charaf, LeCuyer, Tessa E., Baumann, Mathias, Stolley, James Michael, Cremona, Tiziana P., Remold-O′Donnell, Eileen
Format: Artigo
Sprog:Inglês
Udgivet: Society for Leukocyte Biology 2011
Fag:
Spotlight on Leading Edge Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114599/
https://ncbi.nlm.nih.gov/pubmed/21248149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0810461
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