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Thrombospondin-4 regulates fibrosis and remodeling of the myocardium in response to pressure overload
Thrombospondin-4 (TSP-4) expression increases dramatically in hypertrophic and failing hearts in rodent models and in humans. The aim of this study was to address the function of TSP-4 in the heart. TSP-4-knockout (Thbs4(−/−)) and wild-type (WT) mice were subjected to transverse aortic constriction...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Federation of American Societies for Experimental Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3360147/ https://ncbi.nlm.nih.gov/pubmed/22362893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-190728 |
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