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Assessment of circadian rhythms in humans: comparison of real-time fibroblast reporter imaging with plasma melatonin

We compared the period of the rhythm of plasma melatonin, driven by the hypothalamic circadian pacemaker, to in vitro periodicity in cultured peripheral fibroblasts to assess the effects on these rhythms of a polymorphism of PER3 (rs57875989), which is associated with sleep timing. In vitro circadia...

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Autors principals: Hasan, Sibah, Santhi, Nayantara, Lazar, Alpar S., Slak, Ana, Lo, June, von Schantz, Malcolm, Archer, Simon N., Johnston, Jonathan D., Dijk, Derk-Jan
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360144/
https://ncbi.nlm.nih.gov/pubmed/22371527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-201699
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