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Assessment of circadian rhythms in humans: comparison of real-time fibroblast reporter imaging with plasma melatonin

We compared the period of the rhythm of plasma melatonin, driven by the hypothalamic circadian pacemaker, to in vitro periodicity in cultured peripheral fibroblasts to assess the effects on these rhythms of a polymorphism of PER3 (rs57875989), which is associated with sleep timing. In vitro circadia...

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Bibliografische gegevens
Hoofdauteurs: Hasan, Sibah, Santhi, Nayantara, Lazar, Alpar S., Slak, Ana, Lo, June, von Schantz, Malcolm, Archer, Simon N., Johnston, Jonathan D., Dijk, Derk-Jan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Federation of American Societies for Experimental Biology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360144/
https://ncbi.nlm.nih.gov/pubmed/22371527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-201699
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