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P2X4 purinoceptor signaling in chronic pain

ATP, acting via P2 purinergic receptors, is a known mediator of inflammatory and neuropathic pain. There is increasing evidence that the ATP-gated P2X4 receptor (P2X4R) subtype is a locus through which activity of spinal microglia and peripheral macrophages instigate pain hypersensitivity caused by...

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Detalhes bibliográficos
Main Authors: Trang, Tuan, Salter, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360095/
https://ncbi.nlm.nih.gov/pubmed/22528681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-012-9306-7
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