Regulation of Signaling at Regions of Cell-Cell Contact by Endoplasmic Reticulum-Bound Protein-Tyrosine Phosphatase 1B

Protein-tyrosine phosphatase 1B (PTP1B) is a ubiquitously expressed PTP that is anchored to the endoplasmic reticulum (ER). PTP1B dephosphorylates activated receptor tyrosine kinases after endocytosis, as they transit past the ER. However, PTP1B also can access some plasma membrane (PM)-bound substr...

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Main Authors: Haj, Fawaz G., Sabet, Ola, Kinkhabwala, Ali, Wimmer-Kleikamp, Sabine, Roukos, Vassilis, Han, Hong-Mei, Grabenbauer, Markus, Bierbaum, Martin, Antony, Claude, Neel, Benjamin G., Bastiaens, Philippe I.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360045/
https://ncbi.nlm.nih.gov/pubmed/22655028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036633
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