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Intracellular Insulin-like Growth Factor-I Induces Bcl-2 Expression in Airway Epithelial Cells

Bcl-2, a prosurvival protein, regulates programmed cell death during development and repair processes, and can be oncogenic when cell proliferation is deregulated. The present study investigated what factors modulate Bcl-2 expression in airway epithelial cells and identified the pathways involved. M...

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Bibliographic Details
Main Authors: Chand, Hitendra S., Harris, Jennifer Foster, Mebratu, Yohannes, Chen, Yangde, Wright, Paul S., Randell, Scott H., Tesfaigzi, Yohannes
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359962/
https://ncbi.nlm.nih.gov/pubmed/22461702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102673
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