Inhibition of Pim1 Kinase Activation Attenuates Allergen-Induced Airway Hyperresponsiveness and Inflammation

Pim kinases are a family of serine/threonine kinases whose activity can be induced by cytokines involved in allergy and asthma. These kinases play a role in cell survival and proliferation, but have not been examined, to the best of our knowledge, in the development of allergic disease. This study s...

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Hlavní autoři: Shin, Yoo Seob, Takeda, Katsuyuki, Shiraishi, Yoshiki, Jia, Yi, Wang, Meiqin, Jackson, Leila, Wright, A. Dale, Carter, Laura, Robinson, John, Hicken, Erik, Gelfand, Erwin W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359953/
https://ncbi.nlm.nih.gov/pubmed/22074702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0190OC
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