Conflicting Physiological and Genomic Cardiopulmonary Effects of Recruitment Maneuvers in Murine Acute Lung Injury

Low tidal volume ventilation, although promoting atelectasis, is a protective strategy against ventilator-induced lung injury. Deep inflation (DI) recruitment maneuvers restore lung volumes, but potentially compromise lung parenchymal and vascular function via repetitive overdistention. Our objectiv...

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Detalhes bibliográficos
Main Authors: Mekontso Dessap, Armand, Voiriot, Guillaume, Zhou, Tong, Marcos, Elisabeth, Dudek, Steven M., Jacobson, Jeff R., Machado, Roberto, Adnot, Serge, Brochard, Laurent, Maitre, Bernard, Garcia, Joe G. N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359949/
https://ncbi.nlm.nih.gov/pubmed/22135358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0306OC
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