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Interleukin-6 displays lung anti-inflammatory properties and exerts protective hemodynamic effects in a double-hit murine acute lung injury

BACKGROUND: Interleukin 6 (IL-6) is a predictive factor of poor prognosis in patients with acute respiratory distress syndrome (ARDS). However, its acute pulmonary hemodynamic effects and role in lung injury have not been investigated in a clinically relevant murine model of ARDS. METHODS: We used a...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Voiriot, Guillaume, Razazi, Keyvan, Amsellem, Valérie, Tran Van Nhieu, Jeanne, Abid, Shariq, Adnot, Serge, Mekontso Dessap, Armand, Maitre, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397701/
https://ncbi.nlm.nih.gov/pubmed/28424078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0553-6
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