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Hyperoxia-Induced LC3B Interacts with the Fas Apoptotic Pathway in Epithelial Cell Death

Epithelial cell death plays a critical role in hyperoxia-induced lung injury. We investigated the involvement of the autophagic marker microtubule-associated protein-1 light chain-3B (LC3B) in epithelial cell apoptosis after hyperoxia. Prolonged hyperoxia (>95% O(2)), which causes characteristic...

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Autors principals: Tanaka, Akihiko, Jin, Yang, Lee, Seon-Jin, Zhang, Meng, Kim, Hong Pyo, Stolz, Donna B., Ryter, Stefan W., Choi, Augustine M. K.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359946/
https://ncbi.nlm.nih.gov/pubmed/22095627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0415OC
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