Caveolin-1 mediates Fas–BID signaling in hyperoxia-induced apoptosis

Fas-mediated apoptosis is a crucial cellular event. Fas, the Fas-associated death domain, and caspase 8 form the death-inducing signaling complex (DISC). Activated caspase 8 mediates the extrinsic pathways and cleaves cytosolic BID. Truncated BID (tBID) translocates to the mitochondria, facilitates...

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Main Authors: Zhang, Meng, Lee, Seon-Jin, An, ChangHyeok, Xu, Jin-fu, Joshi, Bharat, Nabi, Ivan R., Choi, Augustine M.K., Jin, Yang
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134776/
https://ncbi.nlm.nih.gov/pubmed/21382479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.02.031
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