Resveratrol Neuroprotection in a Chronic Mouse Model of Multiple Sclerosis

Resveratrol is a naturally occurring polyphenol that activates SIRT1, an NAD-dependent deacetylase. SRT501, a pharmaceutical formulation of resveratrol with enhanced systemic absorption, prevents neuronal loss without suppressing inflammation in mice with relapsing experimental autoimmune encephalom...

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Detalhes bibliográficos
Main Authors: Fonseca-Kelly, Zoe, Nassrallah, Mayssa, Uribe, Jorge, Khan, Reas S., Dine, Kimberly, Dutt, Mahasweta, Shindler, Kenneth S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359579/
https://ncbi.nlm.nih.gov/pubmed/22654783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2012.00084
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