Macrophage-Mediated Optic Neuritis Induced by Retrograde Axonal Transport of Spike Gene Recombinant Mouse Hepatitis Virus

After intracranial inoculation, neurovirulent mouse hepatitis virus (MHV) strains induce acute inflammation, demyelination, and axonal loss in the central nervous system. Prior studies using recombinant MHV strains that differ only in the spike gene, which encodes a glycoprotein involved in virus-ho...

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Hlavní autoři: Shindler, Kenneth S., Chatterjee, Dhriti, Biswas, Kaushiki, Goyal, Ashish, Dutt, Mahasweta, Nassrallah, Mayssa, Khan, Reas S., Das Sarma, Jayasri
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association of Neuropathologists, Inc. 2011
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110774/
https://ncbi.nlm.nih.gov/pubmed/21572336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31821da499
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