Inflammasome-Mediated IL-1β Production in Humans with Cystic Fibrosis

BACKGROUND: Inflammation and infection are major determinants of disease severity and consequently, the quality of life and outcome for patients with cystic fibrosis (CF). Interleukin-1 beta (IL-1β) is a key inflammatory mediator. Secretion of biologically active IL-1β involves inflammasome-mediated...

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Detalhes bibliográficos
Main Authors: Tang, Anthony, Sharma, Ashish, Jen, Roger, Hirschfeld, Aaron F., Chilvers, Mark A., Lavoie, Pascal M., Turvey, Stuart E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359311/
https://ncbi.nlm.nih.gov/pubmed/22649552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037689
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