CD24 on thymic antigen presenting cells regulates negative selection of myelin antigen specific T lymphocytes

Negative selection plays a key role in the clonal deletion of autoreactive T cells in the thymus. However, negative selection is incomplete; as high numbers of autoreactive T cells can be detected in normal individuals, mechanisms that regulate negative selection must exist. In this regard, we previ...

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Hauptverfasser: Zhang, Xuejun, Liu, Jin-Qing, Shi, Yun, Reid, Hugh H., Boyd, Richard L., Khattabi, Mazin, El-Omrani, Hani Y., Zheng, Pan, Liu, Yang, Bai, Xue-Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359065/
https://ncbi.nlm.nih.gov/pubmed/22213356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142024
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