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Antigenic drift as a mechanism for tumor evasion of destruction by cytolytic T lymphocytes

It is established that mutations in viral antigenic epitopes, or antigenic drifts, allow viruses to escape recognition by both Ab’s and T lymphocytes. It is unclear, however, whether tumor cells can escape immune recognition via antigenic drift. Here we show that adoptive therapy with both monoclona...

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Autors principals: Bai, Xue-Feng, Liu, Jinqing, Li, Ou, Zheng, Pan, Liu, Yang
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC155049/
https://ncbi.nlm.nih.gov/pubmed/12750398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317656
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