Antigenic drift as a mechanism for tumor evasion of destruction by cytolytic T lymphocytes

It is established that mutations in viral antigenic epitopes, or antigenic drifts, allow viruses to escape recognition by both Ab’s and T lymphocytes. It is unclear, however, whether tumor cells can escape immune recognition via antigenic drift. Here we show that adoptive therapy with both monoclona...

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Pubblicato in:	J Clin Invest
Autori principali:	Bai, Xue-Feng, Liu, Jinqing, Li, Ou, Zheng, Pan, Liu, Yang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2003
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155049/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12750398/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17656
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