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Immunogenicity and Specificity of Norovirus Consensus GII.4 Virus-like Particles in Monovalent and Bivalent Vaccine Formulations

Noroviruses, a major cause of acute gastroenteritis worldwide, present antigenic diversity that must be considered for the development of an effective vaccine. In this study, we explored approaches to increase the broad reactivity of virus-like particle (VLP) norovirus vaccine candidates. The immuno...

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Autori principali: Parra, Gabriel I., Bok, Karin, Taylor, Ross, Haynes, Joel, Sosnovtsev, Stanislav V., Richardson, Charles, Green, Kim Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359014/
https://ncbi.nlm.nih.gov/pubmed/22469864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.03.050
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