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Immunogenicity and Specificity of Norovirus Consensus GII.4 Virus-like Particles in Monovalent and Bivalent Vaccine Formulations

Noroviruses, a major cause of acute gastroenteritis worldwide, present antigenic diversity that must be considered for the development of an effective vaccine. In this study, we explored approaches to increase the broad reactivity of virus-like particle (VLP) norovirus vaccine candidates. The immuno...

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Detalhes bibliográficos
Main Authors: Parra, Gabriel I., Bok, Karin, Taylor, Ross, Haynes, Joel, Sosnovtsev, Stanislav V., Richardson, Charles, Green, Kim Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359014/
https://ncbi.nlm.nih.gov/pubmed/22469864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.03.050
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