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Purkinje cell degeneration, a new neurological mutation in the mouse.

A new autosomal recessive mouse mutation, Purkinje cell degeneration (pcd), is described. Mutants exhibit a moderate ataxia beginning at 3 to 4 weeks of age. The ataxia results from postnatal degeneration of virtually all cerebellar Purkinje cells beginning around 15 to 18 days of age and progressin...

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Bibliographic Details
Main Authors: Mullen, R J, Eicher, E M, Sidman, R L
Format: Artigo
Language:Inglês
Published: 1976
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC335870/
https://ncbi.nlm.nih.gov/pubmed/1061118
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