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High-resolution genetic mapping with pooled sequencing

BACKGROUND: Modern genetics has been transformed by high-throughput sequencing. New experimental designs in model organisms involve analyzing many individuals, pooled and sequenced in groups for increased efficiency. However, the uncertainty from pooling and the challenge of noisy sequencing data de...

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Bibliografiske detaljer
Main Authors: Edwards, Matthew D, Gifford, David K
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358661/
https://ncbi.nlm.nih.gov/pubmed/22537047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-S6-S8
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